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Why does age increase your chances of getting cancer?

Ashley Howard

in Student Loans

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Jeremy Wood on June 27, 2018

In the current model of cancer development, namely the initiaion--promotion of the progression model, cancer development is presumed to be a time-consuming process. The process of sf initiation, which is the process of rendering a single cell susceptible to developing into a malignancy, can take mere milliseconds to seconds, usually with the damage of DNA by chemicals or radiation followed by a round of cell division before the damage can be repaired. The beginning of the cell, then, must be to promote in the appropriate circumstances. If the circumstances are not available, the initiated cell can remain inactive until it is promoted or until he dies. A promotion event always consists in the selective amplification of the initiated cell population. The promoted cell can then divide and proliferate and progression begins. During progression, the body will try to "reshape" the promoted cells to try to make them behave normally again, or kill them through the immune system. The progression is by far the longest of the phases and can be extended by years to decades. The body will initially gain an upper hand and can succeed in the destruction of the promoted cells. However, as the body ages, various mechanisms involved in remodeling and killing these cells become less efficient and promoted cells can proliferate beyond the control of the body, gaining mutations and eventually form a tumor. Therefore, in general, age is almost a prerequisite for people without congenital defects to get the cancer from the normal process of progression takes decades. The body of the defensive machinery becomes less and less efficient at stopping the pre-cancer cells in the body with age.


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